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Computer System Validation Software

Computer system validation (CSV) software for FDA-regulated life sciences

CSV software replaces the spreadsheets, Word templates, and stitched-together Jira boards that most GxP validation programs run on today. cGen is AI-native computer system validation software purpose-built for FDA-regulated life sciences — one platform for the whole lifecycle, inspection-ready by default.

One lifecycle. One platform.

URS, FRS, IQ, OQ, PQ, RTM, deviations, CAPA and periodic review all live in one tool. No hand-offs between Word, Excel, SharePoint and email.

AI drafts. Humans approve.

The cGen AI Assistant generates URS items, test scripts, gap analyses and risk assessments — with a qualified human sign-off on every controlled record.

Part 11 & Annex 11 by default

Every record ships with re-auth, meaning, reason, and MFA on the signature; tamper-evident audit trail on every edit; ALCOA++ markers throughout.

What "computer system validation software" actually needs to do

CSV software has one job: prove — in a form an FDA, EMA or MHRA inspector will accept — that a computerized system does what the business says it does, consistently and within specification, throughout its GxP lifecycle. That means user requirement authoring, functional specification, risk-based test planning aligned to GAMP 5 categories, IQ/OQ/PQ execution with evidence capture, requirements traceability, deviation and CAPA handling, periodic review, and inspection-ready evidence packs — all under 21 CFR Part 11 controls for electronic records and signatures.

Most teams still cobble this together across Word, Excel, a document management system, a ticketing tool, and email. That approach was defensible in 2005. In 2026, with the FDA's Computer Software Assurance (CSA) guidance explicitly encouraging risk-based automation and AI-assisted authoring, it is no longer the fastest — or the most defensible — path.

What buyers should look for in modern CSV software

Any tool that calls itself computer system validation software should give you the following out of the box, not as bolt-on modules:

  • Structured URS, FRS, IQ/OQ/PQ authoring with locked execution mode and per-step evidence capture
  • Auto-maintained Requirements Traceability Matrix, exportable audit-ready
  • A GxP application inventory scored against regulator-readiness, not a static spreadsheet
  • Deviations and CAPAs linked back to specific test steps and system records
  • Part 11 / Annex 11 electronic signatures with re-authentication, meaning, reason, and MFA on every signature event
  • Continuous monitoring with real-time analytics against your validated systems — not just a static report on the day of the audit
  • A read-only, watermarked Inspector Mode so auditors get scoped access rather than a war room and a stack of PDFs
  • A migration wizard that can lift 10 years of records out of Kneat, ValGenesis, Veeva Vault, MasterControl or TrackWise without a paid professional-services engagement

How cGen fits

Built for this exact problem

cGen is that platform. It was designed by a 37-year FDA compliance veteran who spent 100+ engagements watching CSV programs go wrong. Every module — validation projects, GxP inventory, the AI Assistant, Inspector Mode, continuous monitoring, the migration wedge — was built to remove one of the failure modes that trip inspections. Pricing is public and transparent, starting at $2,500/month; the AI Assistant is included in every tier, not a paid add-on.

FAQ

Computer System Validation Software — frequently asked questions

CSV software is a platform that documents and evidences that a computerized system used in a GxP-regulated activity — pharmaceutical manufacturing, biotech, medical devices, clinical operations — meets its intended use consistently and reliably. It authors the URS/FRS/IQ/OQ/PQ, maintains the Requirements Traceability Matrix, executes tests with evidence capture, and manages deviations and periodic reviews under 21 CFR Part 11 controls.
cGen

cGen — AI-native computer system validation software for life sciences. Design, validate, and continuously monitor your GxP-regulated systems in one inspection-ready environment.

contact@compligen.ai(833) 916-CGEN(833-916-2436)

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21 CFR Part 11 GAMP 5 SOC 2 Type II EU GMP Annex 11

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