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Cell & Gene Therapy · San Diego, CA

Helix runs per-patient batch validation with vein-to-vein traceability

317

Patient batches validated

0

Chain-of-identity errors

<4 h

Release decision

The challenge

Autologous CGT manufacturer with batch size = 1. Each patient batch needs traceability from apheresis to infusion. Traditional CSV templates do not fit.

The approach

Helix Cell Therapy ran a focused 4-week proof-of-value with cGen, starting from the GxP application inventory. By the end of week two, every system in scope was registered, categorised under GAMP 5, and assigned an owner. The validation projects that were in flight were migrated into the platform during week three. By week four, the team was running the new Inspector Mode against a simulated FDA scenario.

The outcome

Custom CGT validation templates plus cGen AI risk assessor. Per-patient validation runs deterministically. Chain-of-identity and chain-of-custody captured automatically.

"cGen was the only platform we evaluated that did not flinch at batch-size-one. The CGT templates are not a marketing claim — they actually work."

— Dr. Eleanor Voss, VP Manufacturing Sciences, Helix Cell Therapy

What's next

Helix Cell Therapy is rolling cGen out across two additional sites in the next two quarters, and is one of the early-access programme's reference customers for the cGen three-stage rollout.

Could this be your story?

Join the early signup queue and be first to access cGen when we launch.

cGen

cGen — AI-native computer system validation software for life sciences. Design, validate, and continuously monitor your GxP-regulated systems in one inspection-ready environment.

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21 CFR Part 11 GAMP 5 SOC 2 Type II EU GMP Annex 11

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